' 
SCIENTIFIC SCORE
Possibly Effective
Based on 30 Researches
7.5
USERS' SCORE
Good
Based on 8 Reviews
8.6
Supplement Facts
Serving Size: 3 Caplets
Amount Per Serving
%DV
Vitamin D (as D3 Cholecalciferol)
15 mcg (600 IU)
75%
Calcium (as Calcium Carbonate and Calcium Gluconate)
1,000 mg
77%
Magnesium (as Magnesium Oxide and Magnesium Gluconate)
400 mg
95%
Zinc (as Zinc Gluconate and Zinc Citrate)
25 mg
227%
Sodium
10 mg
<1%
Top Medical Research Studies
8
Magnesium improves chest pain outcomes
Effects of oral magnesium therapy on exercise tolerance, exercise-induced chest pain, and quality of life in patients with coronary artery disease.
Strong relevance to CAD management
We examined how oral magnesium might enhance quality of life and reduce exercise-induced chest pain for those with coronary artery disease (CAD). In an impressive multicenter trial, 187 patients were randomly assigned to receive either magnesium supplements or a placebo for six months.
Our findings show that magnesium therapy improved exercise duration and decreased chest pain during exertion. Participants receiving magnesium reported both enhanced exercise tolerance and better quality of life compared to those on a placebo. This suggests that magnesium supplementation could play an important role in managing CAD symptoms.
Our findings show that magnesium therapy improved exercise duration and decreased chest pain during exertion. Participants receiving magnesium reported both enhanced exercise tolerance and better quality of life compared to those on a placebo. This suggests that magnesium supplementation could play an important role in managing CAD symptoms.
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8
Magnesium shows promise for angina
Effect of magnesium sulphate in patients with unstable angina. A double blind, randomized, placebo-controlled study.
Results indicate potential clinical value.
We aimed to understand how a 24-hour infusion of magnesium sulphate affects patients with unstable angina. In a double-blind, placebo-controlled study, 62 patients were monitored for signs of myocardial ischaemia after receiving either magnesium or a placebo.
While both groups showed some ECG changes, the magnesium group had fewer overall ischaemic episodes and lower levels of heart enzyme release. Additionally, magnesium seemed to reduce stress hormone levels. Our findings suggest that magnesium can be a valuable treatment option for unstable angina, but more research is needed to confirm its effectiveness.
While both groups showed some ECG changes, the magnesium group had fewer overall ischaemic episodes and lower levels of heart enzyme release. Additionally, magnesium seemed to reduce stress hormone levels. Our findings suggest that magnesium can be a valuable treatment option for unstable angina, but more research is needed to confirm its effectiveness.
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9
Zinc treatment for angina pectoris
High-dose zinc to terminate angina pectoris: a review and hypothesis for action by ICAM inhibition.
Directly addresses zinc treatment
We delved into an intriguing question: Can high doses of zinc help relieve chest pain caused by angina pectoris? Our research reviewed studies that highlight how zinc may play a role in managing this condition. Angina pectoris often results from arteriosclerosis, where the arteries become narrowed due to cholesterol buildup and other factors.
We discovered that patients with severe atherosclerosis showed promising improvements when treated with high-dose zinc. Specifically, a treatment regimen involved raising serum zinc levels significantly, resulting in symptom relief for many individuals. In one notable case, 12 out of 16 patients experienced measurable benefits, including one patient who also suffered from Raynaud's disease.
Furthermore, our analysis noted that long-term exposure to zinc in the environment correlated with reduced incidence of angina and ischemic events during exercise. Zinc appears to possess antioxidant properties, which may protect against the oxidation of LDL cholesterol, a key player in artery damage. By blocking certain inflammatory factors and promoting better circulation, zinc might enhance heart function and alleviate chest pain.
Based on these findings, we propose that zinc treatment should be considered a fundamental option in both prevention and therapy for atherosclerosis-related chest pain. This could lead to a renewed focus on restoring a healthier cardiac function among those affected by these conditions.
We discovered that patients with severe atherosclerosis showed promising improvements when treated with high-dose zinc. Specifically, a treatment regimen involved raising serum zinc levels significantly, resulting in symptom relief for many individuals. In one notable case, 12 out of 16 patients experienced measurable benefits, including one patient who also suffered from Raynaud's disease.
Furthermore, our analysis noted that long-term exposure to zinc in the environment correlated with reduced incidence of angina and ischemic events during exercise. Zinc appears to possess antioxidant properties, which may protect against the oxidation of LDL cholesterol, a key player in artery damage. By blocking certain inflammatory factors and promoting better circulation, zinc might enhance heart function and alleviate chest pain.
Based on these findings, we propose that zinc treatment should be considered a fundamental option in both prevention and therapy for atherosclerosis-related chest pain. This could lead to a renewed focus on restoring a healthier cardiac function among those affected by these conditions.
Read More
Most Useful Reviews
9.5
Reduced chest pain
This calcium supplement is economical yet effective. It's better absorbed than other brands, and after a year of use, my friend's elderly mother saw significant improvement, with no more complaints of pain.
Read More
9.5
Improved chest pain
This perfectly balanced combination helps with vitamin D deficiency, harmful effects on bones, and alleviates joint pain, getting me back to a healthier state.
Read More
9.5
Improved chest pain
I understand the benefits of combining this with biotin. My hair and nails have improved, and the persistent lower extremity bone pain reduced after starting this supplement. It's a good complex, though the pills are rather large.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 30 Researches
7.5
- All Researches
9.5
Calcium treatment effective for angina
Case Report: Vasospastic angina presenting as phantom odor perception.
Highlights calcium treatment relevance
We looked at the case of a 69-year-old woman experiencing intermittent shortness of breath and chest pain. Interestingly, she also described a peculiar symptom—a phantom odor sensation that preceded her episodes. During an exercise stress echocardiography, she demonstrated abnormal smell perception alongside transient changes in her heart's electrical activity, which indicated possible cardiac issues.
After conducting invasive coronary angiography, no significant blockages were found in her coronary arteries. This led to a diagnosis of vasospastic angina, a condition that can cause chest pain due to spasms in the coronary arteries rather than physical blockages. To alleviate her symptoms, she was started on calcium channel blocker therapy. Thankfully, this treatment helped in resolving her discomfort.
While the study highlights the role of calcium treatment in managing her symptoms effectively, it's essential to note that this isn't a guaranteed solution for everyone with chest pain. Phantom odors as an indicative symptom of cardiovascular issues are quite rare, suggesting a need for healthcare providers to remain vigilant when patients present with atypical symptoms.
After conducting invasive coronary angiography, no significant blockages were found in her coronary arteries. This led to a diagnosis of vasospastic angina, a condition that can cause chest pain due to spasms in the coronary arteries rather than physical blockages. To alleviate her symptoms, she was started on calcium channel blocker therapy. Thankfully, this treatment helped in resolving her discomfort.
While the study highlights the role of calcium treatment in managing her symptoms effectively, it's essential to note that this isn't a guaranteed solution for everyone with chest pain. Phantom odors as an indicative symptom of cardiovascular issues are quite rare, suggesting a need for healthcare providers to remain vigilant when patients present with atypical symptoms.
Read More
9.5
Calcium channels alleviate chest pain
Bilateral isolated coronary ostial stenosis in a middle-aged premenopausal woman with vasospastic angina: a case report.
Relevant but contextually limited
We explored the unusual case of a 50-year-old premenopausal woman suffering from vasospastic angina (VSA), a form of chest pain resulting from coronary artery spasms. Our patient's daily chest pain, triggered by light exertion, led to testing that revealed mild-to-moderate isolated coronary ostial stenosis (ICOS) along with multi-vessel spasms.
Interestingly, despite the severity often associated with ICOS, she experienced considerable relief after starting treatment with calcium channel blockers (CCBs). This finding is significant as it shows how CCB therapy can effectively manage VSA symptoms, leading to alleviation of chest pain without the need for surgical intervention for ICOS—even over a stretch of 24 years.
Notably, follow-up imaging after this duration indicated that ICOS had resolved, suggesting a remarkable possibility of improvement. However, we should remember that while the use of CCBs proved beneficial in this instance, the results highlight the ongoing need for research into the efficacy of different treatments for chest pain.
Interestingly, despite the severity often associated with ICOS, she experienced considerable relief after starting treatment with calcium channel blockers (CCBs). This finding is significant as it shows how CCB therapy can effectively manage VSA symptoms, leading to alleviation of chest pain without the need for surgical intervention for ICOS—even over a stretch of 24 years.
Notably, follow-up imaging after this duration indicated that ICOS had resolved, suggesting a remarkable possibility of improvement. However, we should remember that while the use of CCBs proved beneficial in this instance, the results highlight the ongoing need for research into the efficacy of different treatments for chest pain.
Read More
9.5
Magnesium's unclear role in chest pain
An adolescent with tingling and numbness of hand: gitelman syndrome.
Moderate relevance; combined therapy analyzed
We examined the role of magnesium in treating chest pain, particularly in a case involving a young female with Gitelman syndrome. This patient experienced recurrent chest pain alongside symptoms like tingling and numbness, prompting a thorough investigation into her condition.
Our exploration revealed that magnesium was indeed part of the treatment plan, but it was combined with potassium and amiloride. This combination makes it challenging to determine how much magnesium alone contributed to alleviating the patient's chest pain.
While magnesium is commonly recognized for its various health benefits, in this specific case, we did not see a clear, isolated benefit from it. Instead, the overall treatment approach seemed to require multiple interventions to achieve improvements in symptoms and biochemical markers.
Our exploration revealed that magnesium was indeed part of the treatment plan, but it was combined with potassium and amiloride. This combination makes it challenging to determine how much magnesium alone contributed to alleviating the patient's chest pain.
While magnesium is commonly recognized for its various health benefits, in this specific case, we did not see a clear, isolated benefit from it. Instead, the overall treatment approach seemed to require multiple interventions to achieve improvements in symptoms and biochemical markers.
Read More
9
Vitamin D's role in chest pain
Adult-onset hypophosphatemic osteomalacia associated with Sjogren syndrome: Clinical case report.
Combined treatments noted effectiveness
We investigated the effectiveness of vitamin D in relieving chest pain associated with a complex case of adult-onset hypophosphatemic osteomalacia (HO) in a 47-year-old woman suffering from Sjogren’s syndrome. In this case, the patient experienced progressively worsening pain in the chest, back, and legs, along with muscle weakness, raising questions about the underlying causes and appropriate treatment options.
After examining lab results, radiographic findings, and pathology, the diagnosis of adult-onset HO was confirmed. The treatment regimen included not only vitamin D but also alkalinization, steroids, neutral phosphate, and calcium supplements. Although the combination of treatments resulted in improved outcomes—such as pain relief and increased serum phosphorus levels—it’s difficult to isolate the effect of vitamin D specifically on chest pain, as it was one part of a broader therapeutic approach.
This case highlights the challenges of diagnosing and treating complex conditions like hypophosphatemic osteomalacia, particularly when associated with autoimmune disorders like Sjogren's syndrome. It underscores the importance of considering various factors and the potential interplay of treatments in managing such cases.
After examining lab results, radiographic findings, and pathology, the diagnosis of adult-onset HO was confirmed. The treatment regimen included not only vitamin D but also alkalinization, steroids, neutral phosphate, and calcium supplements. Although the combination of treatments resulted in improved outcomes—such as pain relief and increased serum phosphorus levels—it’s difficult to isolate the effect of vitamin D specifically on chest pain, as it was one part of a broader therapeutic approach.
This case highlights the challenges of diagnosing and treating complex conditions like hypophosphatemic osteomalacia, particularly when associated with autoimmune disorders like Sjogren's syndrome. It underscores the importance of considering various factors and the potential interplay of treatments in managing such cases.
Read More
9
Impact of Vitamin D on Chest Pain
Sternal stress fracture in a middle-aged woman.
Combined treatment effect unclear
We observed a case involving a middle-aged woman who reported persistent chest pain after starting a new weight training routine. Initially, her pain was localized around the right chest area, making it hard to pinpoint the exact cause. Standard examinations, including ultrasound and X-rays, didn’t uncover any issues, leading to further investigation with an MRI.
The MRI revealed swelling in the sternum, indicating a sternal stress fracture. In response to this finding, the patient was prescribed calcium and vitamin D supplements and advised to rest for six weeks. Following her recovery period, she gradually resumed her activities and was pleased to find herself pain-free after four months.
While it’s clear that vitamin D was part of her treatment regimen, we can only speculate on its specific role in alleviating her chest pain because it was combined with calcium. This means we can't definitively state that vitamin D alone was effective in this case.
Overall, this case serves as an interesting insight into the management of stress fractures in the chest area, showing the importance of proper supplementation and rest in recovery.
The MRI revealed swelling in the sternum, indicating a sternal stress fracture. In response to this finding, the patient was prescribed calcium and vitamin D supplements and advised to rest for six weeks. Following her recovery period, she gradually resumed her activities and was pleased to find herself pain-free after four months.
While it’s clear that vitamin D was part of her treatment regimen, we can only speculate on its specific role in alleviating her chest pain because it was combined with calcium. This means we can't definitively state that vitamin D alone was effective in this case.
Overall, this case serves as an interesting insight into the management of stress fractures in the chest area, showing the importance of proper supplementation and rest in recovery.
Read More
User Reviews
USERS' SCORE
Good
Based on 8 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Reduced chest pain
This calcium supplement is economical yet effective. It's better absorbed than other brands, and after a year of use, my friend's elderly mother saw significant improvement, with no more complaints of pain.
9.5
Improved chest pain
This perfectly balanced combination helps with vitamin D deficiency, harmful effects on bones, and alleviates joint pain, getting me back to a healthier state.
9.5
Improved chest pain
I understand the benefits of combining this with biotin. My hair and nails have improved, and the persistent lower extremity bone pain reduced after starting this supplement. It's a good complex, though the pills are rather large.
8.8
Improved chest pain
I had knee pain after exercising and sought calcium supplementation for relief. Initially, I experienced abdominal pain, but switching to morning doses helped. The knee pain gradually improved, likely due to the calcium.
9.5
Stopped chest pain
Since I began taking this, I've noticed remarkable improvement. The pain in my knee has disappeared. I feel grateful for this change.
